In a number of prospective randomized studies, PCDs have been shown to reduce the incidence of both DVT and PE. In addition, PCDs have been shown to have a direct effect on the fibrinolytic pathway that acts to shorten the euglobulin lysis time, increases levels of coagulation cascade inhibitor molecules, and affects the balance of plasminogen activation. Īttacking the long-recognized risk factor of stasis, PCDs have been shown to increase mean and peak femoral venous blood velocities in the lower extremity. The role of intermittent PCDs for prophylaxis against DVT has been studied and increasingly used in general surgery patients, orthopedic patients, and trauma patients. Rogers, MD, University of Vermont Department of Surgery, Fletcher Allen Health Care, 111 Colchester Avenue, Burlington, VT 05401 email: Statement of the Problem The views and opinions of the authors do not necessarily state or reflect those of EAST and shall not be used for advertising or product endorsement purposes.Īddress for reprints: Frederick B. Submitted for publication September 1, 2001.Īny reference in this guideline to a specific commercial product, process, or service by trade name, trademark, or manufacturer does not constitute or imply an endorsement, recommendation, or any favoritism by the authors or EAST. MD Author Informationįrom the University of Vermont, Department of Surgery, Fletcher Allen Health Care (F.B.R.), Burlington, Vermont, Department of Surgery, Lehigh Valley Hospital (M.D.C.), Allentown, Pennsylvania, Department of Surgery, Division of Trauma and Critical Care, University of Southern California (G.V.), Los Angeles, California, Department of Surgery, Emory University School of Medicine, Atlanta, Georgia, and Department of Surgery, Division of Trauma, Critical Care, and Burns, Loyola University Medical Center (F.A.L.), Maywood, Illinois. MD, PhD Velmahos, George MD, PhD Rozycki, Grace MD Luchette, Fred A. Exempt Purpose, Mission, Vision & Goals.Interviews with Research Scholarship & Award Recipients.Equity, Diversity, and Inclusion in Trauma Surgery Practice.Landmark Papers in Trauma and Acute Care Surgery.
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